PENGARUH MUTASI PADA GEN LEPTIN TERHADAP TEBAL LEMAK PUNGGUNG DAN SKOR KONDISI TUBUH PADA SAPI PERANAKAN ONGOLE
(1) Fakultas Peternakan Universitas Padjadjaran
(2) Fakultas Peternakan Universitas Padjadjaran
(3) Fakultas Peternakan Universitas Padjadjaran
(4) Fakultas Peternakan Universitas Padjadjaran
(5) Alumni Fakultas Peternakan Universitas Padjadjaran
(6) BPPT-SP Cijeungjing Ciamis
(*) Corresponding Author
Sari
Mutation on leptin gene affect leptin function as one of the hormones which contribute to body fat deposition. This research aims to determine the effect of R25C and R25H mutations on the leptin gene toward back fat thickness and Body Condition Score (BCS) in Ongole Grade cattle. The study was conducted with a quasi-experimental method, using completely randomized design. The treatments in this study were genotypes differences was, namely CC, TT and AA. This research used sixthteen heads of Ongole Grade Cattle aged ± 2 years, and was reared for 60 days intensively. The feed consisted of forage and concentrate with a ratio of 25: 75, as much as 3% dry matter of body weight and drinking water was given ad libitum. The backfat thickness was estimated using ultrasound performed on 4.5-6.5 MHz frequency, with depth of 8.8-13 cm, BCS was assessed visually by using 1 – 5 score. The backfat thickness data were analyzed by variance component and BCS data was analyzed by Kruskal Wallis. The results showed average of backfat thickness CC, TT and AA genotype were 3.14 mm, 2.9 mm and 3.57 mm, respectively. The body condition score for CC, TT and AA genotype were 3.54, 3.63 and 3.46 respectively. The Mutation of leptin gene on R25C and R25H have not effect to backfat thickness and body condition score in PO cattle.
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Aditia , E.L., R. Priyanto, M. Baihaq, B.W. Putra1 dan M. Ismail. 2013. Performa Produksi Sapi Bali Dan Peranakan Ongole Yang Digemukan Dengan Pakan Berbasis Sorghum. Jurnal Ilmu Produksi dan Teknologi Hasil Peternakan. Vol. 01 No. 3: 155-159
Altiner Aysen , Isil Sahin , Tanay Bilal, Handan Aydin Vural. 2017. Effect Of Garcinia Cambogia Extract On Serum Leptin, Ghrelin, Adiponectin And Insulin Levels And Body Weights In Rats Fed With High Lipid Diet. Slov Vet Res 2018; 55 (1): 13 -21
Barendse WJ, Bunch RJ dan Harrison BE. 2005. The leptin C73T missense mutation is not associated with marbling and fatness traits in a large gene mapping experiment in Australian cattle. Animal Genetics 36:71-93
Bluher, S., Mantzoros CS. 2009. Leptin in Humans: Lessons From Translational Research. Am J Clin Nutr. Mar;89(3):991S-7S.
Corva PM, Fernández Macedo G V., Soria LA, Papaleo Mazzucco J, Motter M, Villarreal EL, Schor A, Mezzadra CA, Melucci LM, Miquel MC. 2009. Effect of leptin gene polymorphisms on growth, slaughter and meat quality traits of grazing Brangus steers. Genet Mol Res. 8:105-116.
Crews, D. H., J. D. Nkrumah, J. Yu and S. S. Moore. 2004. Association of single nucleotide polymorphisms in the bovine leptin gene with feedlot and carcass characteristics of crossbred steers. Can. J. Anim. Sci. 84:749-750
Fortes, M. R. S., Curi, R. A., Chardulo, L. A. L., Silveira, A. C., Assumpção, M. E. O. D., Visintin, J. A., & Oliveira, H. N. de. (2009). Bovine gene polymorphisms related to fat deposition and meat tenderness. Genetics and Molecular Biology, 32(1), 75–82.
Handiwirawan E. dan B. Tiesnamurti. 2015. Pertambahan Bobot Badan Sapi Bali dan PO yang Digemukkan Berdasarkan Skor Temperamen. Prosiding Seminar Nasional Teknologi Peternakan dan Veteriner 2015: 27-33.
Holtenius, K., S. Agenäs, C. Delavaud, and Y. Chilliard. 2003. Effects of feeding intensity during the dry period. Part 2. Metabolic and hormonal responses. J. Dairy Sci. 86:883–891.
Jakaria, H. Khasanah, R. Priyanto, M. Baihaqi, dan M. F. Ulum. 2017. Prediction of Meat Quality in Bali Cattle Using Ultrasound Imaging. Journal of the Indonesian Tropical Animal Agriculture. Vol. 42 (2) : 59-65.
Kononoff, P. J., H. M. Deobald, E. L. Stewart, A. D. Laycock, dan F. L. S. Marquess. 2005. The Effect of A Leptin Single Nucleotide Polymorphism on Quality Grade, Yield Grade, and Carcass Weight of Beef Cattle. J. Anim. Sci. 83 : 927-932.
Locher, L., S. Häussler, L. Laubenthal, S. P. Singh, J. Winkler, A. Kinoshita, Á. Kenéz, J. Rehage, K. Huber, H. Sauerwein, and S. Dänicke. 2015. Effect of increasing body condition on key regulators of fat metabolism in subcutaneous adipose tissue depot and circulation of nonlactating dairy cows. J. Dairy Sci. 98:1057–1068.
Nkrumah JD, Li C, Basarab JA, Guercio S, Meng Y, Murdoch BM, Hansen C, Moore SS. 2003. Association of a single nucleotide polymorphism in the bovine leptin gene with feed intake, feed efficiency, growth, feeding behaviour, carcass quality and body composition. Can J Anim Sci. 84:211-219.
Priyanto R, A. Asnafiah, E.L. Aditia, M. Baihaqi dan M. Ismail. 2015. Peningkatan Produksi dan Kualitas Daging Sapi Lokal Melalui Penggemukan Berbasis Serealia pada Taraf Energi yang Berbeda. Jurnal Ilmu Pertanian Indonesia (JIPI). Vol. 20 (2): 108114.
Robinson, D. L., L. M. Cafe, dan W. A. McKiernan. 2014. Heritability of Muscle Score and Genetic and Phenotypic Relationships with Weight, Fatness and Eye Muscle Area in Beef Cattle. J. Animal Production Science. Vol. 54 (9) : 1443-1448.
Sellick, G. S., Wayne S. P., Chris A. M., Neil G. C., Allan M. C., Herman W. R., dan Cynthia B. 2007. Effect of Myostatin F94L on Carcass Yield in Cattle. J. Animal Genetics. Vol 38 (5) : 440 – 446.
Shin, S. C dan E. R Chung. 2007. Association of SNP Marker in the Leptin Gene with Carcass and Meat Quality Traits in Korean Cattle. Division of Animal Science and Resources. Asian-Aust, J. Anim. Sci. Vol. 20, No. 1 : 1-6.
Woronuk, G.N., F.L. Marquess, S.T. James, J. Palmer, T . Berryere, H. Deobald., S. Howie, and P.J. Kononoff.2012. Association of leptin genotypes with beef cattle characteristics. Anim. Genet: 1–
DOI: http://dx.doi.org/10.31602/zmip.v46i1.4185
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